Relationship between seminal plasma cytokine levels and asthenozoospermia in infertile men

Background . Violation of male fertility can have various causes, one which is a decrease in sperm motility. In the pathogenesis asthenozoospermia, some bioactive substances, particular cytokines, may be involved. Aim To estimate number most studied cytokines to date ejaculate infertile men with normozoospermia and patients asthenozoospermia. Materials methods We examined 38 10 comparable age. All participants study were performed spermogram an analysis determine amount seminal plasma, such as interleukins 1β, 2, 4–8, 10, 12, 13, 17, G-CSF, GM-CSF, interferon γ, MCP-1, MIP-1β tumor necrosis factor α. Then, using nonparametric statistics, relationship between level above presence asthenozoospermia was analyzed. Results As result, we able find out that there concentration interleukin 6, 8 Conclusion Further research needed assess whether these inflammatory mediators potential relevance for use targets treatment infertility.